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En condiciones de sobreexpresin de NNMT, esta reaccin consume nicotinamida (un precursor del NAD+) y agota reservas de SAM, alterando el equilibrio metablico celular

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Patients are encouraged to discuss all potential treatments with their healthcare provider to ensure safety and efficacy

This selectivity, combined with its ability to efficiently cross cellular membranes, makes it an invaluable research tool for dissecting the specific contributions of NNMT to metabolic regulation